General Information

Bioprocess Engineering Research Group is the research group under the Department. It serves primarily as a link between the University and industry. It is well equipped with facilities capable of providing services to the industries.

It aims to promote and provide research and consultancy work and serves as a catalyst in the discharge of these task. The group also organises from time to time, workshops and seminars to provide a platform to exchange information.

The group focuses on areas such as:

1) Molecular Biology and Protein Engineering

2) Fermentation Technology

3) Animal Tissue Culture

4) Membrane Technology

5) Biochemical Reaction

6) Phytochemical and pharmaceutical

7) Food Engineering

8) Process and Control

9) Computer simulation

10)Enzyme kinetics

11) Protein purification

RESEARCH ACTIVITIES IN THE DEPARTMENT

IRPA RM8

1) Optimization of Cyclodextrin Glucanotransferase Production Using Sago Starch as Carbon Source (MOHD. NAZLEE FAISAL MD GHAZALI)

2) Development of A Specific Recombinant Beta-Cyclodextrin Glucanotransferase (CGTase) from Locally Isolated Bacteria TSI (ASSOC. PROF. DR ROSLI MD. ILLIAS)

3) Assessment of Metyyl Hydroxy Chalcone Polymer (MHCP) from Cinamomum Zeylanicum as Insulin Potentiating Activity (IPA) using a New Cell Cultured Method (Dr. FADZILAH ADIBAH ABD. MAJID)

4) Study of Environmentally Friendly Natural Bio-Pesticide Rotenone for Agricultural and Horticultural Application (PROF. DR. MOHAMAD ROJI SARMIDI)

5) Production of Composite Hollow Fiber Membranes for Bioseparations (DR. ANI IDRIS)

6) Production of Enzymatic Glucose Biosensors (DR. AZILA ABD. AZIZ)

7) Development and Optimization of Microbial Biopolymer Production (DR. FIRDAUSI RAZALI)

8) Synthesis of 2-O-p-D Glucopyyranosyl L-ascorbic Acid by Cyclomaltodextrin Glucanotransferase from Bacillus sp (ROSHANIDA A. RAHMAN)

9) Cloning and Expression if Pullulanase Gene from Locally Isolated Bacillus sp (NIK AZMI NIK MAHMOOD)

10) The Development and Optimization of Processes for the Expression of Sialylated Recombinant Human Therapeutic (DR. BADARULHISAM ABDUL RAHMAN)

IRPA RM7

1) Pilot scale production of efficient technique for deodorissation of cocoa butter (PROF. DR. MOHD. ROJI SARMIDI)

2) Pilot scale production of antibiotic : G-Amino-Penicillanic Acid (PROF. DR. MOHD. ROJI SARMIDI)

3) Purification and characterization of Anti-Thrombin protein from local leeches (Hirudinaria Manillensis) (FAZILAH ABD. LATIF)

4)Production Of Sodium Citrate (PROF. DR. MOHD. ROJI SARMIDI)

5) Antithrombin gene expression with baculovirus infected cells and yeast for future alternatives in large-scale of medical protein production (FAZILAH ABD. LATIF)

6) Site birected mutagenesis of the xylenese gene from clone pCR2A of Pacillus umi lus PJ 19 (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

7) Development of an Integrated Bio-Refinery for Sarawak Forestry Product (PROF. DR. MOHD. ROJI SARMIDI)

8) Isolating, Cloning, Sequencing and Expression of Cyclomaltodextrin lucanotransferase Gene from Bacillus (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

9) Construction of cDNA Library of Hirudin and Manipulation o Polyhedrin for Hirudin Production (NORMAH NORBIB)

10) Pilot Scale Production of Instant SoySource Powder Using Spray Dryer (PROF. DR. MOHD. ROJI SARMIDI)

11) Optimization of Infection Coryza Vaccine Production in Laboratory Scale Fermenter (PROF. DR. MOHD. ROJI SARMIDI)

12) Development of a DNA Vaccine Against Infectious Coryza in Chickens (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

13) Enzymatic and Molecur Studies or Bacterial Cycloterin Glycosyltransferase (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

14) Purification and Characterization of Cylodextrin Gluconotransferase from Locally Isolated Alkalophilic Bactena GI (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

SHORT-TERM RESEARCH GRANT

1)Purification of natural food colourant from buah keduduk (PROF. DR. MOHD. ROJI SARMIDI)

2)Production of alpha (1-6) ghcosidase dan alpha-amylase (FAZILAH ABD. LATIF)

3)Tissue culture technology: Production of monoclonal antibody (MOHD. NAZLEE KAMAL)

4)Production of Hirudin protein (FAZILAH ABD. LATIF)

5)Production of 6-aminopenicillanic acid (6-APA) (PROF. DR. MOHD. ROJI SARMIDI)

6)Production of instant fruit powders by spray drying (YI YI KHAING)

7)Utilization of domestic raw materials as fermentation media (MUJAHID)

8)Purification of penicillin G from fermentation broth (PROF. DR. MOHD. ROJI SARMIDI)

9)Production of Recombinant Xylanase (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

10)Screening For Biomaterial Product From Thermophilic Microorganism (ASSOC. PROF. DR. ROSLI MD. ILLIAS)

11)Modeling And Simulation Of Enzymatic Reaction (ROSLINA RASHID)

12)Biocenversion of Sludge to Commercial Animal Feeds (IDA IDAYU MUHAMMAD)

13)Isolation and Characterization of Adhesive Proties from Green Mussel (Perna Veridis) (SYED ANUAR FAU'AD SYED MUHAMMAD)

14)Enantioselective synthesis of (-) menthyl - Laurate (DR. LEE CHEW TIN)

15)Production and Testing of Ultrafiltratoin Hollow Fiber Membranes (DR. ANI IDRIS)

16)Hydrodynamic Effect on Hybridoma Cell Lines in Serum Free Media (DR. FADZILAH ADIBAH ABDUL MAJID)

17)The Development and Improvement of Animal Cell Culture (DR. FADZILAH ADIBAH ABDUL MAJID)

18)Development of a Membrane Enzyme Reactor for Cyclodextrin Synthesis (MOHD. NAZLEE FAISAL MD. GHAZALI)

19)Model Development for Characterisation of Ultrafiltration and Reverse Osmosis (DR. ANI IDRIS)

20) Bioprocess Approaches In Improving Xanthan Gum Production in Bacterial Culture (DR. FIRDAUSI RAZALI)

21) Enzyme Purification And Characterization of Recombinant 3-Hydroxybutyrate (NIK AZMI NIK MAHMOOD)

22) The optimization of the enzyme immobilization methods for amperometric glucose biosensors (DR. AZILA ABD. AZIZ)

23) Development of biosensor technology for detecting specific contaminants in
environment and agriculture - National Biotechnology Directorate (DR. AZILA ABD. AZIZ)

24) Hydrolysis of Palm Olein to Oleic Acid in a Recirculated Packed Bed Reactor (DR. LEE CHEW TIN)